You'd be surprised. Sometimes pcbs fry due to just poor design and not lightning bolts. The pcb for the ac adapter for my digital camera fried because of those stupid flip-prongs. Apparently the connection wasn't very solid with them causing the pcb to overstress which made a big power trace bubble and break. I repaired the huge broken trace, replaced the flipping prongs with a regular power cord, and it's worked fine for years this way.
I'm not certain if fuses are meant for surges or something shorting.
The one time I suffered a lightning bolt damage the electricity went straight through my 1974 pioneer amp without damaging everything and fried the sound card in my computer that the amp was plugged into.